Tumor Necrosis Factor alpha (TNF-α) is a central cytokine regulating inflammation, immune response, and programmed cell death. Dysregulated TNF-α signaling underlies numerous pathological conditions, including rheumatoid arthritis, inflammatory bowel disease, psoriasis, and sepsis. Accurate detection and modulation of TNF-α are critical for mechanistic and translational studies in immune-mediated diseases. Catalina’s TNF-α antibodies have been rigorously validated, ensuring precise analysis of TNF-α expression, signaling pathways, and cytokine interactions. These antibodies are optimized for research in immunopathology and inflammation biology.